BDBM107164 US8592426, 13

SMILES: Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1cnc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F

InChI Key: InChIKey=JKQWZANTQIVDTL-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107164   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kininogen-1 (Homo sapiens (Human))	BDBM107164 (US8592426, 13) Show SMILES Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1cnc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F Show InChI InChI=1S/C22H18ClF4N7O2/c1-34-32-18(31-33-34)16-13(7-12(23)8-14(16)24)11-6-10-2-3-15(17(10)28-9-11)29-19(35)21(4-5-21)30-20(36)22(25,26)27/h6-9,15H,2-5H2,1H3,(H,29,35)(H,30,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	9.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Kininogen-1 (Homo sapiens (Human))	BDBM107164 (US8592426, 13) Show SMILES Cn1nnc(n1)-c1c(F)cc(Cl)cc1-c1cnc2C(CCc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F Show InChI InChI=1S/C22H18ClF4N7O2/c1-34-32-18(31-33-34)16-13(7-12(23)8-14(16)24)11-6-10-2-3-15(17(10)28-9-11)29-19(35)21(4-5-21)30-20(36)22(25,26)27/h6-9,15H,2-5H2,1H3,(H,29,35)(H,30,36)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair