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SMILES: Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCOc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F

InChI Key: InChIKey=BRUUOQFUWNUOGV-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107165   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kininogen-1 (Homo sapiens (Human))	BDBM107165 (US8592426, 14) Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCOc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F Show InChI InChI=1S/C24H19ClF4N4O4/c1-11-30-20(33-37-11)19-15(9-13(25)10-16(19)26)12-2-3-14-17(4-7-36-18(14)8-12)31-21(34)23(5-6-23)32-22(35)24(27,28)29/h2-3,8-10,17H,4-7H2,1H3,(H,31,34)(H,32,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	212	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Kininogen-1 (Homo sapiens (Human))	BDBM107165 (US8592426, 14) Show SMILES Cc1nc(no1)-c1c(F)cc(Cl)cc1-c1ccc2C(CCOc2c1)NC(=O)C1(CC1)NC(=O)C(F)(F)F Show InChI InChI=1S/C24H19ClF4N4O4/c1-11-30-20(33-37-11)19-15(9-13(25)10-16(19)26)12-2-3-14-17(4-7-36-18(14)8-12)31-21(34)23(5-6-23)32-22(35)24(27,28)29/h2-3,8-10,17H,4-7H2,1H3,(H,31,34)(H,32,35)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	24.8	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair