BDBM107198 US8592426, 48

SMILES: COc1cc(on1)C(=O)NC1(CC1)C(=O)NC1COc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1

InChI Key: InChIKey=RQIRBNSHBCLESE-UHFFFAOYSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107198   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bradykinin-1 Receptor (Homo sapiens (Human))	BDBM107198 (US8592426, 48) Show SMILES COc1cc(on1)C(=O)NC1(CC1)C(=O)NC1COc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1 Show InChI InChI=1S/C26H21ClFN5O6/c1-12-29-23(33-38-12)22-16(8-14(27)9-17(22)28)13-3-4-15-18(11-37-19(15)7-13)30-25(35)26(5-6-26)31-24(34)20-10-21(36-2)32-39-20/h3-4,7-10,18H,5-6,11H2,1-2H3,(H,30,35)(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	23.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Bradykinin-1 Receptor (Homo sapiens (Human))	BDBM107198 (US8592426, 48) Show SMILES COc1cc(on1)C(=O)NC1(CC1)C(=O)NC1COc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1 Show InChI InChI=1S/C26H21ClFN5O6/c1-12-29-23(33-38-12)22-16(8-14(27)9-17(22)28)13-3-4-15-18(11-37-19(15)7-13)30-25(35)26(5-6-26)31-24(34)20-10-21(36-2)32-39-20/h3-4,7-10,18H,5-6,11H2,1-2H3,(H,30,35)(H,31,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair