BDBM107202 US8592426, 52

SMILES: Cc1cc(on1)C(=O)NC1(COC1)C(=O)N[C@H]1CCc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1

InChI Key: InChIKey=IQUDIMJYXGNLDC-NRFANRHFSA-N

Data: 1 KI  1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 107202   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Kininogen-1 (Homo sapiens (Human))	BDBM107202 (US8592426, 52) Show SMILES Cc1cc(on1)C(=O)NC1(COC1)C(=O)N[C@H]1CCc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1 |r| Show InChI InChI=1S/C27H23ClFN5O5/c1-13-7-22(39-33-13)25(35)32-27(11-37-12-27)26(36)31-21-6-4-15-8-16(3-5-18(15)21)19-9-17(28)10-20(29)23(19)24-30-14(2)38-34-24/h3,5,7-10,21H,4,6,11-12H2,1-2H3,(H,31,36)(H,32,35)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	25.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Binding assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair
Kininogen-1 (Homo sapiens (Human))	BDBM107202 (US8592426, 52) Show SMILES Cc1cc(on1)C(=O)NC1(COC1)C(=O)N[C@H]1CCc2cc(ccc12)-c1cc(Cl)cc(F)c1-c1noc(C)n1 |r| Show InChI InChI=1S/C27H23ClFN5O5/c1-13-7-22(39-33-13)25(35)32-27(11-37-12-27)26(36)31-21-6-4-15-8-16(3-5-18(15)21)19-9-17(28)10-20(29)23(19)24-30-14(2)38-34-24/h3,5,7-10,21H,4,6,11-12H2,1-2H3,(H,31,36)(H,32,35)/t21-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4.30	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann—La Roche Inc. US Patent					Assay Description Calcium mobilization assay using Bradykinin-1 receptor.				US Patent US8592426 (2013) BindingDB Entry DOI: 10.7270/Q2WH2NN0
					More data for this Ligand-Target Pair