BindingDB logo
myBDB logout

null

SMILES: Cn1cc2cc(c(F)cc2n1)C(F)(F)c1nnc2ncc(cn12)-c1cnn(c1)C1CC1

InChI Key: InChIKey=AQGMZCNFBPBJNB-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107317   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Hepatocyte growth factor receptor [1038-1346]


(Homo sapiens (Human))		BDBM107317
PNG
(US9695175, 47)
Show SMILES Cn1cc2cc(c(F)cc2n1)C(F)(F)c1nnc2ncc(cn12)-c1cnn(c1)C1CC1
Show InChI InChI=1S/C20H15F3N8/c1-29-8-11-4-15(16(21)5-17(11)28-29)20(22,23)18-26-27-19-24-6-12(9-30(18)19)13-7-25-31(10-13)14-2-3-14/h4-10,14H,2-3H2,1H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 38n/an/an/an/an/a30



CB THERAPEUTICS INC.

US Patent


Assay Description
Optiplate-384 well plate (PerKinElmer), kinase buffer (50 mM Hepes pH7.5, 25 mM NaCl, 2 mM DTT, 0.01% Tween 20, 5 mM Mg2+, 0.5 mM Mn2+), c-Met kinase...

US Patent US9695175 (2017)


BindingDB Entry DOI: 10.7270/Q28W3BGM
More data for this
Ligand-Target Pair