BDBM107773 US8598155, 9

SMILES: CNc1ncnn2c(CO)nc(-c3cnn(C)c3-c3ccc(cc3)C(F)(F)F)c12

InChI Key: InChIKey=MENGDPGPGCBIDQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 107773   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Homo sapiens phosphodiesterase 2A (PDE2A) (Homo sapiens (Human))	BDBM107773 (US8598155, 9) Show SMILES CNc1ncnn2c(CO)nc(-c3cnn(C)c3-c3ccc(cc3)C(F)(F)F)c12 Show InChI InChI=1S/C18H16F3N7O/c1-22-17-16-14(26-13(8-29)28(16)25-9-23-17)12-7-24-27(2)15(12)10-3-5-11(6-4-10)18(19,20)21/h3-7,9,29H,8H2,1-2H3,(H,22,23,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	0.763	n/a	n/a	n/a	n/a	n/a	n/a
Pfizer Inc. US Patent					Assay Description The activity of the test substances on human full-length PDE2A3 enzyme was determined using the [3H]-cGMP scintillation proximity assay (SPA) modifie...				US Patent US8598155 (2013) BindingDB Entry DOI: 10.7270/Q26T0K8C
					More data for this Ligand-Target Pair