BDBM108082 5‐[4‐(furan‐2‐carbonyl)piperazin‐1‐yl]‐1H‐indole‐ 2,3‐dione (Compound 23)

SMILES: O=C(N1CCN(CC1)c1ccc2NC(=O)C(=O)c2c1)c1ccco1

InChI Key: InChIKey=SQLHGOJAEPSBIN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Chorismate mutase (MTB CM) (Mycobacterium tuberculosis H37Rv)	BDBM108082 (5‐[4‐(furan‐2‐carbonyl)pip...) Show SMILES O=C(N1CCN(CC1)c1ccc2NC(=O)C(=O)c2c1)c1ccco1 Show InChI InChI=1S/C17H15N3O4/c21-15-12-10-11(3-4-13(12)18-16(15)22)19-5-7-20(8-6-19)17(23)14-2-1-9-24-14/h1-4,9-10H,5-8H2,(H,18,21,22)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.88E+4	n/a	n/a	n/a	n/a	n/a	37
Birla Institute of Technology & Science-Pilani, Hyderabad Campus, Shameerpet, R.R. District, Hyderabad, Andhra Pradesh, 500078, India					Assay Description The reaction was initiated by the addition of 150pmoles of enzyme to a mixture of inhibitor (40µM, 20 µM, 10 µM, 5 µM, 1 µM ...				Chem Biol Drug Des 83: 498-506 (2014) Article DOI: 10.1111/cbdd.12265 BindingDB Entry DOI: 10.7270/Q2F76B65
					More data for this Ligand-Target Pair