BDBM108295 US8604046, 75

SMILES: C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(Cc4ccccc4)CC3)C2=O)c(F)c1

InChI Key: InChIKey=PMVGIMUYHZHQJC-IGKIAQTJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108295   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Macaca mulatta (Rhesus macaque))	BDBM108295 (US8604046, 75) Show SMILES C[C@H]1CCCN1[C@H]1CCN(C1)c1ccc(N2CCCC3(CCN(Cc4ccccc4)CC3)C2=O)c(F)c1 |r| Show InChI InChI=1S/C31H41FN4O/c1-24-7-5-16-35(24)27-12-18-34(23-27)26-10-11-29(28(32)21-26)36-17-6-13-31(30(36)37)14-19-33(20-15-31)22-25-8-3-2-4-9-25/h2-4,8-11,21,24,27H,5-7,12-20,22-23H2,1H3/t24-,27-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.0600	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...				US Patent US8604046 (2013) BindingDB Entry DOI: 10.7270/Q2W957TB
					More data for this Ligand-Target Pair