BDBM108304 US8604046, 84

SMILES: C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCNCC3)C2=O)c(c1)C(F)(F)F

InChI Key: InChIKey=PRGGSWBLJSNMLI-SFHVURJKSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108304   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histamine H3 receptor (Macaca mulatta (Rhesus macaque))	BDBM108304 (US8604046, 84) Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCNCC3)C2=O)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C25H35F3N4O/c1-18-3-2-13-31(18)19-6-14-30(15-7-19)20-4-5-22(21(17-20)25(26,27)28)32-16-10-24(23(32)33)8-11-29-12-9-24/h4-5,17-19,29H,2-3,6-16H2,1H3/t18-/m0/s1	UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	0.150	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Sanofi US Patent					Assay Description The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...				US Patent US8604046 (2013) BindingDB Entry DOI: 10.7270/Q2W957TB
					More data for this Ligand-Target Pair