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SMILES: C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCN(CC4CCCC4)CC3)C2=O)c(F)c1

InChI Key: InChIKey=PCUDMIQWRAJEOI-QHCPKHFHSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108316   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Histamine H3 receptor


(Macaca mulatta (Rhesus macaque))		BDBM108316
PNG
(US8604046, 96)
Show SMILES C[C@H]1CCCN1C1CCN(CC1)c1ccc(N2CCC3(CCN(CC4CCCC4)CC3)C2=O)c(F)c1 |r|
Show InChI InChI=1S/C30H45FN4O/c1-23-5-4-15-34(23)25-10-16-33(17-11-25)26-8-9-28(27(31)21-26)35-20-14-30(29(35)36)12-18-32(19-13-30)22-24-6-2-3-7-24/h8-9,21,23-25H,2-7,10-20,22H2,1H3/t23-/m0/s1
UniProtKB/TrEMBL

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UniChem

Similars
US Patent
 0.100n/an/an/an/an/an/an/an/a



Sanofi

US Patent


Assay Description
The compounds of this invention have been demonstrated to displace [3H]- methylhistamine radioligand binding to mammalian cell membranes expressing r...

US Patent US8604046 (2013)


BindingDB Entry DOI: 10.7270/Q2W957TB
More data for this
Ligand-Target Pair