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SMILES: Brc1c(Br)c(Br)c2[nH]c(nc2c1Br)N1CCN2CCC1CC2

InChI Key: InChIKey=HEQVIURRETYACQ-UHFFFAOYSA-N

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   Substructure
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108340   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Serine/threonine-protein kinase pim-1


(Homo sapiens (Human))		BDBM108340
PNG
(US8604217, 350)
Show SMILES Brc1c(Br)c(Br)c2[nH]c(nc2c1Br)N1CCN2CCC1CC2 |THB:8:13:17.18:21.20,(-5.81,1.83,;-4.48,1.06,;-4.48,-.48,;-5.81,-1.25,;-3.14,-1.25,;-3.14,-2.79,;-1.81,-.48,;-.34,-.95,;.56,.29,;-.34,1.54,;-1.81,1.06,;-3.14,1.83,;-3.14,3.37,;2.1,.29,;2.99,1.49,;3.2,-.3,;4,-2.03,;5.81,-2.03,;4.6,-1.12,;2.48,-1.12,;1.85,-2.52,;3.24,-3.37,)|
Show InChI InChI=1S/C14H14Br4N4/c15-8-9(16)11(18)13-12(10(8)17)19-14(20-13)22-6-5-21-3-1-7(22)2-4-21/h7H,1-6H2,(H,19,20)
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Similars
US Patent
n/an/a 32.7n/an/an/an/a7.0n/a



Selvita S.A.

US Patent


Assay Description
Kinase assay was performed using luminescent Kinase-Glo (Promega) system. The Kinase-Glo Luminescent Kinase Assay Platform provides a homogeneous, hi...

US Patent US8604217 (2013)


BindingDB Entry DOI: 10.7270/Q2RJ4H31
More data for this
Ligand-Target Pair