BDBM108351 US8604217, 386

SMILES: Brc1c(Br)c(Br)c2[nH]c(nc2c1Br)N1CCC(CC1)C1CCNCC1

InChI Key: InChIKey=LWPRONDFAJLSGK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108351   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human))	BDBM108351 (US8604217, 386) Show SMILES Brc1c(Br)c(Br)c2[nH]c(nc2c1Br)N1CCC(CC1)C1CCNCC1 Show InChI InChI=1S/C17H20Br4N4/c18-11-12(19)14(21)16-15(13(11)20)23-17(24-16)25-7-3-10(4-8-25)9-1-5-22-6-2-9/h9-10,22H,1-8H2,(H,23,24)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	58.0	n/a	n/a	n/a	n/a	7.0	n/a
Selvita S.A. US Patent					Assay Description Kinase assay was performed using luminescent Kinase-Glo (Promega) system. The Kinase-Glo Luminescent Kinase Assay Platform provides a homogeneous, hi...				US Patent US8604217 (2013) BindingDB Entry DOI: 10.7270/Q2RJ4H31
					More data for this Ligand-Target Pair