BDBM108382 US9695200, 88

SMILES: C=CC(=O)Nc1cccc(c1)-c1cnc2[nH]cc(-c3cn(CC4CC4)c(=O)c4[nH]ccc34)c2c1

InChI Key: InChIKey=ODVWDMJAYSXVOK-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108382   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase C-gamma-1 (Homo sapiens (Human))	BDBM108382 (US9695200, 88) Show SMILES C=CC(=O)Nc1cccc(c1)-c1cnc2[nH]cc(-c3cn(CC4CC4)c(=O)c4[nH]ccc34)c2c1 Show InChI InChI=1S/C27H23N5O2/c1-2-24(33)31-19-5-3-4-17(10-19)18-11-21-22(13-30-26(21)29-12-18)23-15-32(14-16-6-7-16)27(34)25-20(23)8-9-28-25/h2-5,8-13,15-16,28H,1,6-7,14H2,(H,29,30)(H,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	37
Confluence Life Sciences, Inc. US Patent					Assay Description Compounds were serially diluted into DMSO, and then into media to concentrations 10× that of the final assay concentration. Compounds were then added...				US Patent US9695200 (2017) BindingDB Entry DOI: 10.7270/Q20G3H9T
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ITK/TSK (Homo sapiens (Human))	BDBM108382 (US9695200, 88) Show SMILES C=CC(=O)Nc1cccc(c1)-c1cnc2[nH]cc(-c3cn(CC4CC4)c(=O)c4[nH]ccc34)c2c1 Show InChI InChI=1S/C27H23N5O2/c1-2-24(33)31-19-5-3-4-17(10-19)18-11-21-22(13-30-26(21)29-12-18)23-15-32(14-16-6-7-16)27(34)25-20(23)8-9-28-25/h2-5,8-13,15-16,28H,1,6-7,14H2,(H,29,30)(H,31,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Confluence Life Sciences, Inc. US Patent					Assay Description This assay is based on the binding of a proprietary, Alexa Fluor 647-labeled, ATP-competitive kinase inhibitor (kinase tracer-236) to the ITK express...				US Patent US9695200 (2017) BindingDB Entry DOI: 10.7270/Q20G3H9T
					More data for this Ligand-Target Pair