BDBM108693 US8604016, 273::US9938267, Cmpd ID 273

SMILES: Fc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(F)c4)s3)s2)c1

InChI Key: InChIKey=DDEFZXOTJNLSOH-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108693   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108693 (US8604016, 273 | US9938267, Cmpd ID 273) Show SMILES Fc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(F)c4)s3)s2)c1 Show InChI InChI=1S/C24H22F2N6O2S2/c25-17-7-3-5-15(11-17)13-19(33)27-23-31-29-21(35-23)9-1-2-10-22-30-32-24(36-22)28-20(34)14-16-6-4-8-18(26)12-16/h3-8,11-12H,1-2,9-10,13-14H2,(H,27,31,33)(H,28,32,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description No preinc (Column 4).				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108693 (US8604016, 273 | US9938267, Cmpd ID 273) Show SMILES Fc1cccc(CC(=O)Nc2nnc(CCCCc3nnc(NC(=O)Cc4cccc(F)c4)s3)s2)c1 Show InChI InChI=1S/C24H22F2N6O2S2/c25-17-7-3-5-15(11-17)13-19(33)27-23-31-29-21(35-23)9-1-2-10-22-30-32-24(36-22)28-20(34)14-16-6-4-8-18(26)12-16/h3-8,11-12H,1-2,9-10,13-14H2,(H,27,31,33)(H,28,32,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair