BDBM108712 US8604016, 292::US9938267, Cmpd ID 292

SMILES: Fc1ccccc1CC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3F)s2)s1

InChI Key: InChIKey=CQYHPMYVWDQQRA-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108712   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108712 (US8604016, 292 | US9938267, Cmpd ID 292) Show SMILES Fc1ccccc1CC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3F)s2)s1 Show InChI InChI=1S/C24H22F2N6O2S2/c25-17-9-3-1-7-15(17)13-19(33)27-23-31-29-21(35-23)11-5-6-12-22-30-32-24(36-22)28-20(34)14-16-8-2-4-10-18(16)26/h1-4,7-10H,5-6,11-14H2,(H,27,31,33)(H,28,32,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description No preinc (Column 4).				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108712 (US8604016, 292 | US9938267, Cmpd ID 292) Show SMILES Fc1ccccc1CC(=O)Nc1nnc(CCCCc2nnc(NC(=O)Cc3ccccc3F)s2)s1 Show InChI InChI=1S/C24H22F2N6O2S2/c25-17-9-3-1-7-15(17)13-19(33)27-23-31-29-21(35-23)11-5-6-12-22-30-32-24(36-22)28-20(34)14-16-8-2-4-10-18(16)26/h1-4,7-10H,5-6,11-14H2,(H,27,31,33)(H,28,32,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair