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BDBM108852 US8604016, 432

SMILES: O=C(Cc1cccc(CNC(=O)c2ccccc2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1

InChI Key: InChIKey=YTYFGUNQXSXKAS-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 108852   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glutaminase kidney isoform, mitochondrial


(Homo sapiens (Human))
BDBM108852
PNG
(US8604016, 432)
Show SMILES O=C(Cc1cccc(CNC(=O)c2ccccc2)c1)Nc1nnc(CCCCc2ccc(NC(=O)Cc3ccccc3)nn2)s1
Show InChI InChI=1S/C34H33N7O3S/c42-30(21-24-10-3-1-4-11-24)36-29-19-18-28(38-39-29)16-7-8-17-32-40-41-34(45-32)37-31(43)22-25-12-9-13-26(20-25)23-35-33(44)27-14-5-2-6-15-27/h1-6,9-15,18-20H,7-8,16-17,21-23H2,(H,35,44)(H,36,39,42)(H,37,41,43)
PDB
MMDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 2n/an/an/an/an/an/a



Calithera Biosciences Inc.

US Patent


Assay Description
Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...


US Patent US8604016 (2013)


BindingDB Entry DOI: 10.7270/Q2CC0ZBW
More data for this
Ligand-Target Pair