null

SMILES: Oc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F

InChI Key: InChIKey=LDTYJJGNGZMPPN-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 108956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108956 (US8604016, 538 | US9938267, Cmpd ID 538) Show SMILES Oc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F Show InChI InChI=1S/C26H25FN6O3S/c27-20-12-10-18(14-21(20)34)16-24(36)29-26-33-32-25(37-26)9-5-4-8-19-11-13-22(31-30-19)28-23(35)15-17-6-2-1-3-7-17/h1-3,6-7,10-14,34H,4-5,8-9,15-16H2,(H,28,31,35)(H,29,33,36)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM108956 (US8604016, 538 | US9938267, Cmpd ID 538) Show SMILES Oc1cc(CC(=O)Nc2nnc(CCCCc3ccc(NC(=O)Cc4ccccc4)nn3)s2)ccc1F Show InChI InChI=1S/C26H25FN6O3S/c27-20-12-10-18(14-21(20)34)16-24(36)29-26-33-32-25(37-26)9-5-4-8-19-11-13-22(31-30-19)28-23(35)15-17-6-2-1-3-7-17/h1-3,6-7,10-14,34H,4-5,8-9,15-16H2,(H,28,31,35)(H,29,33,36)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair