BDBM109009 US8604016, 591::US9938267, Cmpd ID 591

SMILES: CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)OCCF)c3)nn2)s1)c1ccccc1

InChI Key: InChIKey=CYNFZSRTCXSKDS-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 109009   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109009 (US8604016, 591 | US9938267, Cmpd ID 591) Show SMILES CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)OCCF)c3)nn2)s1)c1ccccc1 Show InChI InChI=1S/C31H34FN7O4S/c1-21(24-10-3-2-4-11-24)29(41)35-30-39-38-28(44-30)13-6-5-12-25-14-15-26(37-36-25)34-27(40)19-22-8-7-9-23(18-22)20-33-31(42)43-17-16-32/h2-4,7-11,14-15,18,21H,5-6,12-13,16-17,19-20H2,1H3,(H,33,42)(H,34,37,40)(H,35,39,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Amgen					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				J Med Chem 51: 1681-94 (2008) BindingDB Entry DOI: 10.7270/Q2JS9SQV
					More data for this Ligand-Target Pair
Glutaminase kidney isoform, mitochondrial (Homo sapiens (Human))	BDBM109009 (US8604016, 591 | US9938267, Cmpd ID 591) Show SMILES CC(C(=O)Nc1nnc(CCCCc2ccc(NC(=O)Cc3cccc(CNC(=O)OCCF)c3)nn2)s1)c1ccccc1 Show InChI InChI=1S/C31H34FN7O4S/c1-21(24-10-3-2-4-11-24)29(41)35-30-39-38-28(44-30)13-6-5-12-25-14-15-26(37-36-25)34-27(40)19-22-8-7-9-23(18-22)20-33-31(42)43-17-16-32/h2-4,7-11,14-15,18,21H,5-6,12-13,16-17,19-20H2,1H3,(H,33,42)(H,34,37,40)(H,35,39,41)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
Calithera Biosciences Inc. US Patent					Assay Description Compounds were assessed for their ability to inhibit the enzymatic activity of a recombinant form of Glutaminase 1 (GAC) using a biochemical assay th...				US Patent US8604016 (2013) BindingDB Entry DOI: 10.7270/Q2CC0ZBW
					More data for this Ligand-Target Pair