BDBM10908 3-(dimethylamino)-4-[(3,5-dimethylphenyl)methyl]-5-ethyl-6-methyl-1,2-dihydropyridin-2-one::3-Dimethylamino-4-(3,5-dimethylbenzyl)-5-ethyl-6-methylpyridin-2(1H)-one::4-benzyl pyridinone derivative 27

SMILES: CCc1c(C)[nH]c(=O)c(N(C)C)c1Cc1cc(C)cc(C)c1

InChI Key: InChIKey=FHQCHOTUQBIXHY-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 10908   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM10908 (3-(dimethylamino)-4-[(3,5-dimethylphenyl)methyl]-5...) Show SMILES CCc1c(C)[nH]c(=O)c(N(C)C)c1Cc1cc(C)cc(C)c1 Show InChI InChI=1S/C19H26N2O/c1-7-16-14(4)20-19(22)18(21(5)6)17(16)11-15-9-12(2)8-13(3)10-15/h8-10H,7,11H2,1-6H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Uppsala University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase				J Med Chem 51: 2648-56 (2008) Article DOI: 10.1021/jm7012198 BindingDB Entry DOI: 10.7270/Q2V40XZG
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM10908 (3-(dimethylamino)-4-[(3,5-dimethylphenyl)methyl]-5...) Show SMILES CCc1c(C)[nH]c(=O)c(N(C)C)c1Cc1cc(C)cc(C)c1 Show InChI InChI=1S/C19H26N2O/c1-7-16-14(4)20-19(22)18(21(5)6)17(16)11-15-9-12(2)8-13(3)10-15/h8-10H,7,11H2,1-6H3,(H,20,22)	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	8.0	37
Institut Curie					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				J Med Chem 43: 3949-62 (2000) Article DOI: 10.1021/jm0009437 BindingDB Entry DOI: 10.7270/Q2V12315
					More data for this Ligand-Target Pair