BDBM109155 US8609852, 62

SMILES: CC[C@H](C)Nc1ccc(c[nH+]1)C#Cc1csc(C)n1

InChI Key: InChIKey=LAPLDUHQSRFIHM-NSHDSACASA-O

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109155   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metabotropic glutamate receptor 5 (Rattus norvegicus (Rat))	BDBM109155 (US8609852, 62) Show SMILES CC[C@H](C)Nc1ccc(c[nH+]1)C#Cc1csc(C)n1 |r| Show InChI InChI=1S/C15H17N3S/c1-4-11(2)17-15-8-6-13(9-16-15)5-7-14-10-19-12(3)18-14/h6,8-11H,4H2,1-3H3,(H,16,17)/p+1/t11-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	11	-10.8	n/a	n/a	n/a	n/a	n/a	n/a	25
Merck Sharp & Dohme Corp. US Patent					Assay Description Binding assays were performed as described in Schaffhauser H, Richards J G, Cartmell J, Chaboz S, Kemp J A, Klingelschmidt A, Messer J, Stadler H, Wo...				US Patent US8609852 (2013) BindingDB Entry DOI: 10.7270/Q27M06K3
					More data for this Ligand-Target Pair