BDBM109203 US8604028, 65

SMILES: CC1=NC2=C(C(C1[N+]#[C-])c1cc3c(NC(=O)c4ccccc4)nccc3o1)C(=O)OC2

InChI Key: InChIKey=VFNOPSPJFUZFBO-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109203   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM109203 (US8604028, 65) Show SMILES CC1=NC2=C(C(C1[N+]#[C-])c1cc3c(NC(=O)c4ccccc4)nccc3o1)C(=O)OC2 |c:3,t:1| Show InChI InChI=1S/C23H16N4O4/c1-12-20(24-2)19(18-15(26-12)11-30-23(18)29)17-10-14-16(31-17)8-9-25-21(14)27-22(28)13-6-4-3-5-7-13/h3-10,19-20H,11H2,1H3,(H,25,27,28)	PDB MMDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	142	n/a	n/a	n/a	n/a	7.0	32
Bayer Intellectual Property GmbH US Patent					Assay Description Tyrosine kinase activity assay (NADH Read-Out)using human c-Met protein (Invitrogen, Carlsbad, Calif., USA). The amount of phosphorylated substrate ...				US Patent US8604028 (2013) BindingDB Entry DOI: 10.7270/Q23T9FVT
					More data for this Ligand-Target Pair