BindingDB logo
myBDB logout

null

SMILES: Cc1ccnc(c1)-n1[nH]cc(-c2cncc(c2)C#N)c1=O

InChI Key: InChIKey=JAGAZUUNNHQHFU-UHFFFAOYSA-N

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109267   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Transmembrane prolyl 4-hydroxylase


(Homo sapiens (Human))		BDBM109267
PNG
(US8609698, 8)
Show SMILES Cc1ccnc(c1)-n1[nH]cc(-c2cncc(c2)C#N)c1=O
Show InChI InChI=1S/C15H11N5O/c1-10-2-3-18-14(4-10)20-15(21)13(9-19-20)12-5-11(6-16)7-17-8-12/h2-5,7-9,19H,1H3
PDB

KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars
US Patent
n/an/a 5.20E+3n/an/an/an/an/an/a



Bayer Intellectual Property GmbH

US Patent


Assay Description
Inhibition of the Activity of HIF Prolyl Hydroxylase is carried out as described [Oehme F., Jonghaus W., Narouz-Ott L., Huetter J., Flamme I., Anal. ...

US Patent US8609698 (2013)


BindingDB Entry DOI: 10.7270/Q2G44NZ8
More data for this
Ligand-Target Pair