BDBM109274 US8609622, 1
SMILES: OC[C@]12CO[C@](O1)([C@H](O)[C@@H](O)[C@@H]2O)c1ccc(Cl)c(Cc2ccc(OCCOC3CC3)cc2)c1
InChI Key: InChIKey=VCZVXZUEEYJYLC-UBCNIHEASA-N
Data: 2 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
sodium-dependent glucose cotransporter 1 (SGLT1) (Mus musculus (Mouse)) | BDBM109274 (US8609622, 1) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | >2.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
sodium-dependent glucose cotransporter 2 (SGLT2) (Mus musculus (Mouse)) | BDBM109274 (US8609622, 1) | PDB Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 9.53 | n/a | n/a | n/a | n/a | n/a | n/a |
Shanghai Hengrui Pharmaceutical Co., Ltd.; Jiangsu Hengrui Medicine Co., Ltd. US Patent | Assay Description Inhibitory activity of the compounds using SGLT1 and SGLT2. | US Patent US8609622 (2013) BindingDB Entry DOI: 10.7270/Q2BC3X6H | |||||||||||
More data for this Ligand-Target Pair |