BDBM109328 US8609666, 48

SMILES: OCCNc1cc(nc2c(nc(nc12)N1CCOCC1)-c1cccc(CO)c1)C(O)=O

InChI Key: InChIKey=OFPBSWQQRHAZMY-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 109328   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform (Homo sapiens (Human))	BDBM109328 (US8609666, 48) Show SMILES OCCNc1cc(nc2c(nc(nc12)N1CCOCC1)-c1cccc(CO)c1)C(O)=O Show InChI InChI=1S/C21H23N5O5/c27-7-4-22-15-11-16(20(29)30)23-19-17(14-3-1-2-13(10-14)12-28)24-21(25-18(15)19)26-5-8-31-9-6-26/h1-3,10-11,27-28H,4-9,12H2,(H,22,23)(H,29,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Merck Serono SA US Patent					Assay Description The efficacy of compounds of the invention in inhibiting the PI3K induced-lipid phosphorylation may be tested in the following binding assay. The ass...				US Patent US8609666 (2013) BindingDB Entry DOI: 10.7270/Q26M35G5
					More data for this Ligand-Target Pair