BDBM110178 3-Amino-4-[3-(4I-methoxyphenyl)-1-phenyl-1H-pyrazol-5-yl)methylene]- 1H-pyrazol-5(4H)-one (1d)

SMILES: COc1ccc(cc1)-c1cc(Cc2c(N)[nH][nH]c2=O)n(n1)-c1ccccc1

InChI Key: InChIKey=ZHQXFKASKCZXCN-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 110178   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Aldose reductase (AR) (Homo sapiens (Human))	BDBM110178 (3-Amino-4-[3-(4I-methoxyphenyl)-1-phenyl-1H-pyrazo...) Show SMILES COc1ccc(cc1)-c1cc(Cc2c(N)[nH][nH]c2=O)n(n1)-c1ccccc1 Show InChI InChI=1S/C20H19N5O2/c1-27-16-9-7-13(8-10-16)18-12-15(11-17-19(21)22-23-20(17)26)25(24-18)14-5-3-2-4-6-14/h2-10,12H,11H2,1H3,(H4,21,22,23,26)	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.70E+3	n/a	n/a	n/a	n/a	6.2	37
Swami Ramanand Teerth Marathwada University, Nanded (MS), India					Assay Description The reaction mixture contained 1 mL of 1 M potassium phosphate buffer (pH 6.2), 0.4 mM lithium sulfate and 5 µM 2-mercaptoethanol, 10 µM DL...				Bioorg Chem 53: 67-74 (2014) Article DOI: 10.1016/j.bioorg.2014.02.002 BindingDB Entry DOI: 10.7270/Q2SF2TTP
					More data for this Ligand-Target Pair