null

SMILES: CC(C)(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCCN1C1CCCC1)C1CCCCC1)C(=O)N1C[C@]2(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)N1CCCC1)C(C)(C)C21CCC1

InChI Key: InChIKey=NWFWLEAQCNXLAB-ZQGBQPHDSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 110264   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Genome polyprotein (Hepatitis C virus (HCV genotype 1a, isolate H))	BDBM110264 (US8613914, 32 | US9206232, 32) Show SMILES CC(C)(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCCN1C1CCCC1)C1CCCCC1)C(=O)N1C[C@]2(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)N1CCCC1)C(C)(C)C21CCC1 |r| Show InChI InChI=1S/C47H75N7O7S/c1-7-32-28-47(32,42(59)51-62(60,61)52-25-15-16-26-52)50-39(56)35-29-46(44(5,6)45(46)23-17-24-45)30-54(35)41(58)37(43(2,3)4)49-40(57)36(31-18-9-8-10-19-31)48-38(55)34-22-13-14-27-53(34)33-20-11-12-21-33/h7,31-37H,1,8-30H2,2-6H3,(H,48,55)(H,49,57)(H,50,56)(H,51,59)/t32-,34+,35+,36+,37-,46-,47-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The inhibitory activity of certain compounds of Table A against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length ...				US Patent US9206232 (2015) BindingDB Entry DOI: 10.7270/Q2M0447H
					More data for this Ligand-Target Pair
Genome polyprotein (Hepatitis C virus)	BDBM110264 (US8613914, 32 | US9206232, 32) Show SMILES CC(C)(C)[C@H](NC(=O)[C@@H](NC(=O)[C@@H]1CCCCN1C1CCCC1)C1CCCCC1)C(=O)N1C[C@]2(C[C@H]1C(=O)N[C@@]1(C[C@H]1C=C)C(=O)NS(=O)(=O)N1CCCC1)C(C)(C)C21CCC1 |r| Show InChI InChI=1S/C47H75N7O7S/c1-7-32-28-47(32,42(59)51-62(60,61)52-25-15-16-26-52)50-39(56)35-29-46(44(5,6)45(46)23-17-24-45)30-54(35)41(58)37(43(2,3)4)49-40(57)36(31-18-9-8-10-19-31)48-38(55)34-22-13-14-27-53(34)33-20-11-12-21-33/h7,31-37H,1,8-30H2,2-6H3,(H,48,55)(H,49,57)(H,50,56)(H,51,59)/t32-,34+,35+,36+,37-,46-,47-/m1/s1	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
Novartis AG US Patent					Assay Description The inhibitory activity of certain compounds against HCV NS3-4A serine protease is determined in a homogenous assay using the full-length NS3-4A prot...				US Patent US8613914 (2013) BindingDB Entry DOI: 10.7270/Q28C9TWW
					More data for this Ligand-Target Pair