null

SMILES: CCn1c(CN(Cc2ccccc2)Cc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12

InChI Key: InChIKey=HYRGWRYSRJVQQM-JQIJEIRASA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 1103   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 1 (Homo sapiens (Human))	BDBM1103 (US10201527, Compound 68 | US10736881, Compound 68 ...) Show SMILES CCn1c(CN(Cc2ccccc2)Cc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C27H28N4O2/c1-2-31-25-15-13-21(14-16-27(32)29-33)17-24(25)28-26(31)20-30(18-22-9-5-3-6-10-22)19-23-11-7-4-8-12-23/h3-17,33H,2,18-20H2,1H3,(H,29,32)/b16-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	n/a
Mei Pharma, Inc. US Patent					Assay Description The assay have been carried out in a 96 well format and the BIOMOL using a fluorescent-based HDAC activity assay.				US Patent US8551988 (2013) BindingDB Entry DOI: 10.7270/Q2BZ64P8
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM1103 (US10201527, Compound 68 | US10736881, Compound 68 ...) Show SMILES CCn1c(CN(Cc2ccccc2)Cc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C27H28N4O2/c1-2-31-25-15-13-21(14-16-27(32)29-33)17-24(25)28-26(31)20-30(18-22-9-5-3-6-10-22)19-23-11-7-4-8-12-23/h3-17,33H,2,18-20H2,1H3,(H,29,32)/b16-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	n/a
MEI Pharma, Inc. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10736881 (2020)
					More data for this Ligand-Target Pair
Histone deacetylase 1 (Homo sapiens (Human))	BDBM1103 (US10201527, Compound 68 | US10736881, Compound 68 ...) Show SMILES CCn1c(CN(Cc2ccccc2)Cc2ccccc2)nc2cc(\C=C\C(=O)NO)ccc12 Show InChI InChI=1S/C27H28N4O2/c1-2-31-25-15-13-21(14-16-27(32)29-33)17-24(25)28-26(31)20-30(18-22-9-5-3-6-10-22)19-23-11-7-4-8-12-23/h3-17,33H,2,18-20H2,1H3,(H,29,32)/b16-14+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	294	n/a	n/a	n/a	n/a	n/a	n/a
MEI PHARMA, INC. US Patent					Assay Description The assay has been carried out in 96 well format and the BIOMOL fluorescent-based HDAC activity assay has been applied. The reaction composed of assa...				US Patent US10201527 (2019) BindingDB Entry DOI: 10.7270/Q2PK0J7F
					More data for this Ligand-Target Pair