BDBM11068 (2R,5S)-N-(4-bromophenyl)-5-{[(2S)-2-cyanopyrrolidin-1-yl]carbonyl}pyrrolidine-2-carboxamide::2-cyanopyrrolidine 18b

SMILES: Brc1ccc(NC(=O)[C@H]2CC[C@H](N2)C(=O)N2CCC[C@H]2C#N)cc1

InChI Key: InChIKey=FIEYAHMLEPRXMZ-ZNMIVQPWSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11068 ((2R,5S)-N-(4-bromophenyl)-5-{[(2S)-2-cyanopyrrolid...) Show SMILES Brc1ccc(NC(=O)[C@H]2CC[C@H](N2)C(=O)N2CCC[C@H]2C#N)cc1 |r| Show InChI InChI=1S/C17H19BrN4O2/c18-11-3-5-12(6-4-11)20-16(23)14-7-8-15(21-14)17(24)22-9-1-2-13(22)10-19/h3-6,13-15,21H,1-2,7-9H2,(H,20,23)/t13-,14+,15-/m0/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	1.31E+3	-7.94	n/a	n/a	n/a	n/a	n/a	7.5	22
Abbott Laboratories					Assay Description The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...				J Med Chem 49: 3520-35 (2006) Article DOI: 10.1021/jm051283e BindingDB Entry DOI: 10.7270/Q2WS8RG1
					More data for this Ligand-Target Pair