BDBM11075 (2S)-1-{[(2S,5R)-5-{[methyl(phenyl)amino]methyl}pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carbonitrile::2-cyanopyrrolidine 19c

SMILES: CN(C[C@H]1CC[C@H](N1)C(=O)N1CCC[C@H]1C#N)c1ccccc1

InChI Key: InChIKey=KSRNYSSAZQEJNJ-PVAVHDDUSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11075   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11075 ((2S)-1-{[(2S,5R)-5-{[methyl(phenyl)amino]methyl}py...) Show SMILES CN(C[C@H]1CC[C@H](N1)C(=O)N1CCC[C@H]1C#N)c1ccccc1 |r| Show InChI InChI=1S/C18H24N4O/c1-21(15-6-3-2-4-7-15)13-14-9-10-17(20-14)18(23)22-11-5-8-16(22)12-19/h2-4,6-7,14,16-17,20H,5,8-11,13H2,1H3/t14-,16+,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	49	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...				J Med Chem 49: 3520-35 (2006) Article DOI: 10.1021/jm051283e BindingDB Entry DOI: 10.7270/Q2WS8RG1
					More data for this Ligand-Target Pair