BDBM11082 (2S)-1-{[(2S,5R)-5-(4-methoxyphenoxymethyl)pyrrolidin-2-yl]carbonyl}pyrrolidine-2-carbonitrile::2-cyanopyrrolidine 21f

SMILES: COc1ccc(OC[C@H]2CC[C@H](N2)C(=O)N2CCC[C@H]2C#N)cc1

InChI Key: InChIKey=FSKIXIBBRJSXJE-KEYYUXOJSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11082   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11082 ((2S)-1-{[(2S,5R)-5-(4-methoxyphenoxymethyl)pyrroli...) Show SMILES COc1ccc(OC[C@H]2CC[C@H](N2)C(=O)N2CCC[C@H]2C#N)cc1 |r| Show InChI InChI=1S/C18H23N3O3/c1-23-15-5-7-16(8-6-15)24-12-13-4-9-17(20-13)18(22)21-10-2-3-14(21)11-19/h5-8,13-14,17,20H,2-4,9-10,12H2,1H3/t13-,14+,17+/m1/s1	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Abbott Laboratories					Assay Description The DPP4 activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and mea...				J Med Chem 49: 3520-35 (2006) Article DOI: 10.1021/jm051283e BindingDB Entry DOI: 10.7270/Q2WS8RG1
					More data for this Ligand-Target Pair