BDBM111509 US8618158, NU8350
SMILES: OC\C=C/COC1(N(Cc2ccc(cc2)[N+]([O-])=O)C(=O)c2ccccc12)c1ccc(Cl)cc1
InChI Key: InChIKey=ZSXCWVPXSODIRG-ARJAWSKDSA-N
Data: 1 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
E3 ubiquitin-protein ligase Mdm2 (Homo sapiens (Human)) | BDBM111509 (US8618158, NU8350) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 402 | n/a | n/a | n/a | n/a | n/a | 25 |
Cancer Research Technology Limited US Patent | Assay Description Streptavidin-coated 96-well plates are used to immobilise a biotin-tagged IP3 p53-derived peptide (MPRFMDYWEGLN). This is a peptide analogue derived ... | US Patent US8618158 (2013) BindingDB Entry DOI: 10.7270/Q27D2STZ | |||||||||||
More data for this Ligand-Target Pair |