null

SMILES: CC(C=C1CCCC(=CC(C)c2ccccc2)C1=O)c1ccccc1

InChI Key: InChIKey=WLLDKGHKJACMCA-UHFFFAOYSA-N

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 111818   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Phospholipase A2 (Homo sapiens (Human))	BDBM111818 ((2E,6E)‐2,6‐bis(2‐phenylpropylid...) Show SMILES CC(C=C1CCCC(=CC(C)c2ccccc2)C1=O)c1ccccc1 |w:2.1,8.8| Show InChI InChI=1S/C24H26O/c1-18(20-10-5-3-6-11-20)16-22-14-9-15-23(24(22)25)17-19(2)21-12-7-4-8-13-21/h3-8,10-13,16-19H,9,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	9.47E+4	n/a	n/a	n/a	n/a	8.0	25
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia					Assay Description Substrate 1,2-bis(heptanoylthio)-glycerophosphocholine and human recombinant PLA2-V were resuspended in assay buffer, and DTNB was dissolved in an aq...				Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM111818 ((2E,6E)‐2,6‐bis(2‐phenylpropylid...) Show SMILES CC(C=C1CCCC(=CC(C)c2ccccc2)C1=O)c1ccccc1 |w:2.1,8.8| Show InChI InChI=1S/C24H26O/c1-18(20-10-5-3-6-11-20)16-22-14-9-15-23(24(22)25)17-19(2)21-12-7-4-8-13-21/h3-8,10-13,16-19H,9,14-15H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.03E+4	n/a	n/a	n/a	n/a	7.0	20
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia					Assay Description The assay buffer contained 100 mM KHPO4 (pH 7.0), 2 mM EDTA and 2.5 mM reduced GSH. 100 µL of reaction buffer containing human recombinant mPGES...				Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V
					More data for this Ligand-Target Pair
Prostaglandin G/H synthase 1 (Ovis aries (Sheep))	BDBM111818 ((2E,6E)‐2,6‐bis(2‐phenylpropylid...) Show SMILES CC(C=C1CCCC(=CC(C)c2ccccc2)C1=O)c1ccccc1 |w:2.1,8.8| Show InChI InChI=1S/C24H26O/c1-18(20-10-5-3-6-11-20)16-22-14-9-15-23(24(22)25)17-19(2)21-12-7-4-8-13-21/h3-8,10-13,16-19H,9,14-15H2,1-2H3	PDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.94E+5	n/a	n/a	n/a	n/a	8.0	37
Universiti Kebangsaan Malaysia, Jalan Raja Muda Abdul Aziz, 50300, Kuala Lumpur, Malaysia					Assay Description Reaction mixture containing 100 mM Tris-HCl buffer (pH 8) and COX-1 (ovine) or COX-2 (human recombinant) was preincubated for 10 min in a water bath ...				Chem Biol Drug Des 83: 670-81 (2014) Article DOI: 10.1111/cbdd.12280 BindingDB Entry DOI: 10.7270/Q26H4G2V
					More data for this Ligand-Target Pair