BDBM112697 US8629158, 10

SMILES: FC(F)(F)c1ccc(cn1)-c1ccn(-c2ccc3c4C5CCC(Cc4[nH]c3c2)N5)c(=O)c1

InChI Key: InChIKey=RWSRFWUAVDKPJQ-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112697   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Melanin-concentrating hormone receptor (Homo sapiens (Human))	BDBM112697 (US8629158, 10) Show SMILES FC(F)(F)c1ccc(cn1)-c1ccn(-c2ccc3c4C5CCC(Cc4[nH]c3c2)N5)c(=O)c1 |THB:17:18:28:20.21,25:24:28:20.21| Show InChI InChI=1S/C24H19F3N4O/c25-24(26,27)21-6-1-14(12-28-21)13-7-8-31(22(32)9-13)16-3-4-17-19(11-16)30-20-10-15-2-5-18(29-15)23(17)20/h1,3-4,6-9,11-12,15,18,29-30H,2,5,10H2	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	22.7	-10.4	n/a	n/a	n/a	n/a	n/a	7.4	25
Albany Molecular Research, Inc. US Patent					Assay Description Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...				US Patent US8629158 (2014) BindingDB Entry DOI: 10.7270/Q24J0CS7
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