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BDBM112732 US8629158, 47

SMILES: Cn1c2CC3CCC(N3)c2c2ccc(nc12)-n1ccc(OCc2ccc(Cl)cc2F)cc1=O

InChI Key: InChIKey=AQXAZJWIECLKLQ-UHFFFAOYSA-N

Data: 1 KI

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112732   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Melanin-concentrating hormone receptor


(Homo sapiens (Human))		BDBM112732
PNG
(US8629158, 47)
Show SMILES Cn1c2CC3CCC(N3)c2c2ccc(nc12)-n1ccc(OCc2ccc(Cl)cc2F)cc1=O
Show InChI InChI=1S/C25H22ClFN4O2/c1-30-21-11-16-4-6-20(28-16)24(21)18-5-7-22(29-25(18)30)31-9-8-17(12-23(31)32)33-13-14-2-3-15(26)10-19(14)27/h2-3,5,7-10,12,16,20,28H,4,6,11,13H2,1H3
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Similars
US Patent
 14 -10.7n/an/an/an/an/a7.425



Albany Molecular Research, Inc.

US Patent


Assay Description
Evaluation of the affinity of compounds for the human MCH-1 receptor was accomplished using 4-(3,4,5-tritritiumbenzyloxy)-1-(1-(2-(pyrrolidin-1-yl)et...

US Patent US8629158 (2014)


BindingDB Entry DOI: 10.7270/Q24J0CS7
More data for this
Ligand-Target Pair