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SMILES: C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(cc1)C(F)(F)F

InChI Key: InChIKey=UBHGKLVUABXZBR-APPDUMDISA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 112856   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Androgen receptor


(Rattus norvegicus (Rat))		BDBM112856
PNG
(US8629167, 68)
Show SMILES C[C@H](O)[C@@H](Nc1ccc([N+]#[C-])c(Cl)c1C)c1nnc(o1)-c1ccc(cc1)C(F)(F)F |r|
Show InChI InChI=1S/C20H16ClF3N4O2/c1-10-14(8-9-15(25-3)16(10)21)26-17(11(2)29)19-28-27-18(30-19)12-4-6-13(7-5-12)20(22,23)24/h4-9,11,17,26,29H,1-2H3/t11-,17+/m0/s1
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Similars
US Patent
n/an/a 12n/an/an/an/an/an/a



Radius Health, Inc.

US Patent


Assay Description
In order to demonstrate the utility of the compounds of this invention, an androgen receptor binding assay was performed wherein many of the compound...

US Patent US8629167 (2014)


BindingDB Entry DOI: 10.7270/Q2GT5KTX
More data for this
Ligand-Target Pair