BDBM11317 1,8-dihydroxy-9H-xanthen-9-one::Xanthenone-related compound
SMILES: Oc1cccc2oc3cccc(O)c3c(=O)c12
InChI Key: InChIKey=XWPUJQLPABYIPZ-UHFFFAOYSA-N
Data: 1 KI
PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Casein Kinase II (Zea mays (Maize)) | BDBM11317 (1,8-dihydroxy-9H-xanthen-9-one | Xanthenone-relate...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | >4.00E+4 | >-5.94 | n/a | n/a | n/a | n/a | n/a | 7.5 | 22 |
University of Padova | Assay Description In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam... | J Biol Chem 278: 1831-6 (2003) Article DOI: 10.1074/jbc.M209367200 BindingDB Entry DOI: 10.7270/Q2GH9G5K | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (docked) |