BDBM113421 US9682940, 57

SMILES: FC(F)(F)c1cccc(c1)-n1nc(C2CCN(CC2)S(=O)(=O)C(F)(F)F)c2cc(ccc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1

InChI Key: InChIKey=DTMHOAKFSWTBNX-UHFFFAOYSA-N

Data: 2 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 113421   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cannabinoid receptor 2 (Homo sapiens (Human))	BDBM113421 (US9682940, 57) Show SMILES FC(F)(F)c1cccc(c1)-n1nc(C2CCN(CC2)S(=O)(=O)C(F)(F)F)c2cc(ccc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C33H25Cl2F6N3O2S/c34-25-9-4-20(5-10-25)30(21-6-11-26(35)12-7-21)23-8-13-29-28(18-23)31(22-14-16-43(17-15-22)47(45,46)33(39,40)41)42-44(29)27-3-1-2-24(19-27)32(36,37)38/h1-13,18-19,22,30H,14-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM113421 (US9682940, 57) Show SMILES FC(F)(F)c1cccc(c1)-n1nc(C2CCN(CC2)S(=O)(=O)C(F)(F)F)c2cc(ccc12)C(c1ccc(Cl)cc1)c1ccc(Cl)cc1 Show InChI InChI=1S/C33H25Cl2F6N3O2S/c34-25-9-4-20(5-10-25)30(21-6-11-26(35)12-7-21)23-8-13-29-28(18-23)31(22-14-16-43(17-15-22)47(45,46)33(39,40)41)42-44(29)27-3-1-2-24(19-27)32(36,37)38/h1-13,18-19,22,30H,14-17H2	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	474	n/a	n/a	n/a	n/a
Janssen Pharmaceutica NV US Patent					Assay Description CB1 and CB2 receptors are Gi-coupled GPCR. Activation of CB1 and CB2 receptors results in a decrease in cAMP production. An inverse agonist of the CB...				US Patent US9682940 (2017) BindingDB Entry DOI: 10.7270/Q2M61HD7
					More data for this Ligand-Target Pair