BDBM114605 2-[4-(2,5-difluorobenzyl)piperazino]pyrimidine::2-[4-[(2,5-difluorophenyl)methyl]-1-piperazinyl]pyrimidine::2-[4-[(2,5-difluorophenyl)methyl]piperazin-1-yl]pyrimidine::2-[4-[[2,5-bis(fluoranyl)phenyl]methyl]piperazin-1-yl]pyrimidine::SR-01000208233::SR-01000208233-3::cid_782050
SMILES: Fc1ccc(F)c(CN2CCN(CC2)c2ncccn2)c1
InChI Key: InChIKey=ZUXYDLKOVYXPNF-UHFFFAOYSA-N
Data: 2 EC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (5HT2A) (Mus musculus (Mouse)) | BDBM114605 (2-[4-(2,5-difluorobenzyl)piperazino]pyrimidine | 2...) | PDB UniProtKB/SwissProt UniProtKB/TrEMBL GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 7.61E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Affiliation: The Scripps Research Institute, TSRI Assa... | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q24B2ZZ6 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM114605 (2-[4-(2,5-difluorobenzyl)piperazino]pyrimidine | 2...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | n/a | n/a | 9.25E+4 | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Assay Provider: Laura Bohn External Assay ID: OPRM1_AC... | PubChem Bioassay (2013) BindingDB Entry DOI: 10.7270/Q2833QNG | |||||||||||
More data for this Ligand-Target Pair |