BDBM11549 2-[(3,5-dichloro-1,1-biphenyl-4-yl)methyl]-N-hydroxyisothiazolidine-3-carboxamide 1,1-dioxide::2-{[4-(3,5-dichlorophenyl)phenyl]methyl}-N-hydroxy-1,1-dioxo-1,2-thiazolidine-3-carboxamide::Sultam Hydroxamate 15b

SMILES: ONC(=O)C1CCS(=O)(=O)N1Cc1ccc(cc1)-c1cc(Cl)cc(Cl)c1

InChI Key: InChIKey=LLVLFZAKVKFNSB-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 11549   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Matrix metalloproteinase-9 (Homo sapiens (Human))	BDBM11549 (2-[(3,5-dichloro-1,1-biphenyl-4-yl)methyl]-N-hydro...) Show SMILES ONC(=O)C1CCS(=O)(=O)N1Cc1ccc(cc1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H16Cl2N2O4S/c18-14-7-13(8-15(19)9-14)12-3-1-11(2-4-12)10-21-16(17(22)20-23)5-6-26(21,24)25/h1-4,7-9,16,23H,5-6,10H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>2.13E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...				J Med Chem 47: 2981-3 (2004) Article DOI: 10.1021/jm049833g BindingDB Entry DOI: 10.7270/Q29W0CQB
					More data for this Ligand-Target Pair
72 kDa type IV collagenase (Homo sapiens (Human))	BDBM11549 (2-[(3,5-dichloro-1,1-biphenyl-4-yl)methyl]-N-hydro...) Show SMILES ONC(=O)C1CCS(=O)(=O)N1Cc1ccc(cc1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H16Cl2N2O4S/c18-14-7-13(8-15(19)9-14)12-3-1-11(2-4-12)10-21-16(17(22)20-23)5-6-26(21,24)25/h1-4,7-9,16,23H,5-6,10H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>3.33E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...				J Med Chem 47: 2981-3 (2004) Article DOI: 10.1021/jm049833g BindingDB Entry DOI: 10.7270/Q29W0CQB
					More data for this Ligand-Target Pair
Interstitial collagenase (Homo sapiens (Human))	BDBM11549 (2-[(3,5-dichloro-1,1-biphenyl-4-yl)methyl]-N-hydro...) Show SMILES ONC(=O)C1CCS(=O)(=O)N1Cc1ccc(cc1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H16Cl2N2O4S/c18-14-7-13(8-15(19)9-14)12-3-1-11(2-4-12)10-21-16(17(22)20-23)5-6-26(21,24)25/h1-4,7-9,16,23H,5-6,10H2,(H,20,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>4.95E+3	>-7.23	n/a	n/a	n/a	n/a	n/a	7.5	25
Bristol-Myers Squibb Company					Assay Description The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...				J Med Chem 47: 2981-3 (2004) Article DOI: 10.1021/jm049833g BindingDB Entry DOI: 10.7270/Q29W0CQB
					More data for this Ligand-Target Pair
Collagenase 3 (Homo sapiens (Human))	BDBM11549 (2-[(3,5-dichloro-1,1-biphenyl-4-yl)methyl]-N-hydro...) Show SMILES ONC(=O)C1CCS(=O)(=O)N1Cc1ccc(cc1)-c1cc(Cl)cc(Cl)c1 Show InChI InChI=1S/C17H16Cl2N2O4S/c18-14-7-13(8-15(19)9-14)12-3-1-11(2-4-12)10-21-16(17(22)20-23)5-6-26(21,24)25/h1-4,7-9,16,23H,5-6,10H2,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	>5.03E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company					Assay Description The enzymatic activities of MMPs were determined with recombinant human version catalytic domains and a fluorogenic peptide substrate. Fluorescence m...				J Med Chem 47: 2981-3 (2004) Article DOI: 10.1021/jm049833g BindingDB Entry DOI: 10.7270/Q29W0CQB
					More data for this Ligand-Target Pair