BDBM11563 1b-ortho-Me::5-(aminomethyl)-6-(2-methylphenyl)-2-phenylpyrimidin-4-amine::Aminomethylpyrimidine 1ba

SMILES: Cc1ccccc1-c1nc(nc(N)c1CN)-c1ccccc1

InChI Key: InChIKey=BCCBGRQUXTZXBP-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11563   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11563 (1b-ortho-Me | 5-(aminomethyl)-6-(2-methylphenyl)-2...) Show SMILES Cc1ccccc1-c1nc(nc(N)c1CN)-c1ccccc1 Show InChI InChI=1S/C18H18N4/c1-12-7-5-6-10-14(12)16-15(11-19)17(20)22-18(21-16)13-8-3-2-4-9-13/h2-10H,11,19H2,1H3,(H2,20,21,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	7.5	22
Hoffmann-La Roche Inc.					Assay Description DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...				Bioorg Med Chem Lett 14: 1491-3 (2004) Article DOI: 10.1016/j.bmcl.2004.01.019 BindingDB Entry DOI: 10.7270/Q22B8W7M
					More data for this Ligand-Target Pair