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SMILES: COc1ccccc1-c1nc(nc(N)c1CN)-c1ccccc1

InChI Key: InChIKey=WATHNSGVYPMULE-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11569   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dipeptidyl peptidase 4


(Homo sapiens (Human))		BDBM11569
PNG
(1b-ortho-OMe | 5-(aminomethyl)-6-(2-methoxyphenyl)...)
Show SMILES COc1ccccc1-c1nc(nc(N)c1CN)-c1ccccc1
Show InChI InChI=1S/C18H18N4O/c1-23-15-10-6-5-9-13(15)16-14(11-19)17(20)22-18(21-16)12-7-3-2-4-8-12/h2-10H,11,19H2,1H3,(H2,20,21,22)
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MMDB

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n/an/a 1.50E+3n/an/an/an/a7.522



Hoffmann-La Roche Inc.



Assay Description
DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...

Bioorg Med Chem Lett 14: 1491-3 (2004)


Article DOI: 10.1016/j.bmcl.2004.01.019
BindingDB Entry DOI: 10.7270/Q22B8W7M
More data for this
Ligand-Target Pair