BDBM11576 1b-meta-CF3::5-(aminomethyl)-2-phenyl-6-[3-(trifluoromethyl)phenyl]pyrimidin-4-amine::Aminomethylpyrimidine 1bn

SMILES: NCc1c(N)nc(nc1-c1cccc(c1)C(F)(F)F)-c1ccccc1

InChI Key: InChIKey=GKIKUZLNVVHWNQ-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11576   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dipeptidyl peptidase 4 (Homo sapiens (Human))	BDBM11576 (1b-meta-CF3 | 5-(aminomethyl)-2-phenyl-6-[3-(trifl...) Show SMILES NCc1c(N)nc(nc1-c1cccc(c1)C(F)(F)F)-c1ccccc1 Show InChI InChI=1S/C18H15F3N4/c19-18(20,21)13-8-4-7-12(9-13)15-14(10-22)16(23)25-17(24-15)11-5-2-1-3-6-11/h1-9H,10,22H2,(H2,23,24,25)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Hoffmann-La Roche Inc.					Assay Description DPP-IV inhibitors were measured for their ability to inhibit DPP-IV mediated cleavage of Ala-Pro-7-amido-4-trifluoromethylcoumarin in a fluorogenic a...				Bioorg Med Chem Lett 14: 1491-3 (2004) Article DOI: 10.1016/j.bmcl.2004.01.019 BindingDB Entry DOI: 10.7270/Q22B8W7M
					More data for this Ligand-Target Pair