BDBM116198 US8637502, 17
SMILES: Fc1ccc2[nH]c(=O)c(=O)n(C3CCN(CC3)C3CCCCCCC3)c2c1
InChI Key: InChIKey=WLVVKUAGVPJCQB-UHFFFAOYSA-N
Data: 2 KI
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nociceptin receptor (Homo sapiens (Human)) | BDBM116198 (US8637502, 17) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 11.5 | -10.1 | n/a | n/a | n/a | n/a | n/a | 7.4 | 4 |
Purde Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto... | US Patent US8637502 (2014) BindingDB Entry DOI: 10.7270/Q2P55M54 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM116198 (US8637502, 17) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 2.50E+3 | -7.64 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Purde Pharma L.P.; Shionogi & Co., Ltd. US Patent | Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphi... | US Patent US8637502 (2014) BindingDB Entry DOI: 10.7270/Q2P55M54 | |||||||||||
More data for this Ligand-Target Pair |