BDBM116201 US8637502, 24

SMILES: NC(=O)Cn1c2ccccc2n(C2CCN(CC2)C2Cc3cccc4cccc2c34)c(=O)c1=O

InChI Key: InChIKey=YCKODQWAIKYAQB-UHFFFAOYSA-N

Data: 4 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 116201   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nociceptin receptor (Homo sapiens (Human))	BDBM116201 (US8637502, 24) Show SMILES NC(=O)Cn1c2ccccc2n(C2CCN(CC2)C2Cc3cccc4cccc2c34)c(=O)c1=O Show InChI InChI=1S/C27H26N4O3/c28-24(32)16-30-21-9-1-2-10-22(21)31(27(34)26(30)33)19-11-13-29(14-12-19)23-15-18-7-3-5-17-6-4-8-20(23)25(17)18/h1-10,19,23H,11-16H2,(H2,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	453	-8.04	n/a	n/a	n/a	n/a	n/a	7.4	4
Purde Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description ORL-1 Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human opioid receptor-like receptor (ORL-1) (Recepto...				US Patent US8637502 (2014) BindingDB Entry DOI: 10.7270/Q2P55M54
					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM116201 (US8637502, 24) Show SMILES NC(=O)Cn1c2ccccc2n(C2CCN(CC2)C2Cc3cccc4cccc2c34)c(=O)c1=O Show InChI InChI=1S/C27H26N4O3/c28-24(32)16-30-21-9-1-2-10-22(21)31(27(34)26(30)33)19-11-13-29(14-12-19)23-15-18-7-3-5-17-6-4-8-20(23)25(17)18/h1-10,19,23H,11-16H2,(H2,28,32)	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	3.30E+3	-7.47	n/a	n/a	n/a	n/a	n/a	7.4	25
Purde Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description μ-Opioid Receptor Binding Assay Procedures: Radioligand dose-displacement binding assays for μ-opioid receptors used 0.2 nM[3H]-diprenorphi...				US Patent US8637502 (2014) BindingDB Entry DOI: 10.7270/Q2P55M54
					More data for this Ligand-Target Pair
Delta-type opioid receptor (Homo sapiens (Human))	BDBM116201 (US8637502, 24) Show SMILES NC(=O)Cn1c2ccccc2n(C2CCN(CC2)C2Cc3cccc4cccc2c34)c(=O)c1=O Show InChI InChI=1S/C27H26N4O3/c28-24(32)16-30-21-9-1-2-10-22(21)31(27(34)26(30)33)19-11-13-29(14-12-19)23-15-18-7-3-5-17-6-4-8-20(23)25(17)18/h1-10,19,23H,11-16H2,(H2,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	5.45E+3	-7.18	n/a	n/a	n/a	n/a	n/a	7.4	25
Purde Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description δ-Receptor Binding Assay Procedures: Radioligand dose-displacement assays used 0.2 nM [3H]-Naltrindole (NEN; 33.0 Ci/mmole) with 10-20 μg m...				US Patent US8637502 (2014) BindingDB Entry DOI: 10.7270/Q2P55M54
					More data for this Ligand-Target Pair
Kappa-type opioid receptor (Homo sapiens (Human))	BDBM116201 (US8637502, 24) Show SMILES NC(=O)Cn1c2ccccc2n(C2CCN(CC2)C2Cc3cccc4cccc2c34)c(=O)c1=O Show InChI InChI=1S/C27H26N4O3/c28-24(32)16-30-21-9-1-2-10-22(21)31(27(34)26(30)33)19-11-13-29(14-12-19)23-15-18-7-3-5-17-6-4-8-20(23)25(17)18/h1-10,19,23H,11-16H2,(H2,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	6.95E+3	-6.54	n/a	n/a	n/a	n/a	n/a	7.4	4
Purde Pharma L.P.; Shionogi & Co., Ltd. US Patent					Assay Description κ-Opioid Receptor Binding Assay Procedures: Membranes from recombinant HEK-293 cells expressing the human kappa opioid receptor (kappa) (cloned ...				US Patent US8637502 (2014) BindingDB Entry DOI: 10.7270/Q2P55M54
					More data for this Ligand-Target Pair