BDBM117067 US8664230, 3

SMILES: Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(OC3CCOCC3)c2n1

InChI Key: InChIKey=PEHVSVSYATZDNB-UHFFFAOYSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 117067   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
PI3-kinase class I (Homo sapiens (Human))	BDBM117067 (US8664230, 3) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(OC3CCOCC3)c2n1 Show InChI InChI=1S/C23H18ClF2N5O4S/c24-22-19(31-36(32,33)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(30-17)23(29-12-28-18)35-15-5-7-34-8-6-15/h1-4,9-12,15,31H,5-8H2	PDB UniProtKB/SwissProt UniProtKB/TrEMBL antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform (Homo sapiens (Human))	BDBM117067 (US8664230, 3) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(OC3CCOCC3)c2n1 Show InChI InChI=1S/C23H18ClF2N5O4S/c24-22-19(31-36(32,33)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(30-17)23(29-12-28-18)35-15-5-7-34-8-6-15/h1-4,9-12,15,31H,5-8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform (Homo sapiens (Human))	BDBM117067 (US8664230, 3) Show SMILES Fc1ccc(c(F)c1)S(=O)(=O)Nc1cc(cnc1Cl)-c1ccc2ncnc(OC3CCOCC3)c2n1 Show InChI InChI=1S/C23H18ClF2N5O4S/c24-22-19(31-36(32,33)20-4-1-14(25)10-16(20)26)9-13(11-27-22)17-2-3-18-21(30-17)23(29-12-28-18)35-15-5-7-34-8-6-15/h1-4,9-12,15,31H,5-8H2	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	<1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Asan Foundation US Patent					Assay Description The PI3 Kinase Activity/Inhibitor Assay is a competitive assay used for the fast and sensitive quantitation of activity of the four class I PI3 kinas...				US Patent US8664230 (2014) BindingDB Entry DOI: 10.7270/Q2N58K1R
					More data for this Ligand-Target Pair