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BDBM11764 2-[(4-chlorobenzene)[(2-chlorophenyl)methyl]sulfonamido]-N-hydroxypropanamide::hydroxamate deriv. B10

SMILES: CC(N(Cc1ccccc1Cl)S(=O)(=O)c1ccc(Cl)cc1)C(=O)NO

InChI Key: InChIKey=UOZODUVCBQCNBC-UHFFFAOYSA-N

Data: 1 KI

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11764   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Collagenase (ChC)


(Clostridium histolyticum)
BDBM11764
PNG
(2-[(4-chlorobenzene)[(2-chlorophenyl)methyl]sulfon...)
Show SMILES CC(N(Cc1ccccc1Cl)S(=O)(=O)c1ccc(Cl)cc1)C(=O)NO
Show InChI InChI=1S/C16H16Cl2N2O4S/c1-11(16(21)19-22)20(10-12-4-2-3-5-15(12)18)25(23,24)14-8-6-13(17)7-9-14/h2-9,11,22H,10H2,1H3,(H,19,21)
PDB
MMDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
35n/an/an/an/an/an/an/an/a



Universita degli Studi di Firenze



Assay Description
The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...


Bioorg Med Chem 8: 637-45 (2000)


Article DOI: 10.1016/s0968-0896(99)00316-8
BindingDB Entry DOI: 10.7270/Q2542KT3
More data for this
Ligand-Target Pair