BDBM11781 2-{[(2-chlorophenyl)methyl](3,5-dichloro-2-hydroxybenzene)sulfonamido}-N-hydroxypropanamide::hydroxamate deriv. B27

SMILES: CC(N(Cc1ccccc1Cl)S(=O)(=O)c1cc(Cl)cc(Cl)c1O)C(=O)NO

InChI Key: InChIKey=MCYOSHJFNPMCKS-UHFFFAOYSA-N

Data: 1 KI

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 11781   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Collagenase (ChC) (Clostridium histolyticum)	BDBM11781 (2-{[(2-chlorophenyl)methyl](3,5-dichloro-2-hydroxy...) Show SMILES CC(N(Cc1ccccc1Cl)S(=O)(=O)c1cc(Cl)cc(Cl)c1O)C(=O)NO Show InChI InChI=1S/C16H15Cl3N2O5S/c1-9(16(23)20-24)21(8-10-4-2-3-5-12(10)18)27(25,26)14-7-11(17)6-13(19)15(14)22/h2-7,9,22,24H,8H2,1H3,(H,20,23)	PDB MMDB UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universita degli Studi di Firenze					Assay Description The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...				Bioorg Med Chem 8: 637-45 (2000) Article DOI: 10.1016/s0968-0896(99)00316-8 BindingDB Entry DOI: 10.7270/Q2542KT3
					More data for this Ligand-Target Pair