BDBM118049 US8637558, 77

SMILES: OC1=NC(=O)C(S1)=Cc1cc(F)c(OCCC2CCCCC2)c(Cl)c1

InChI Key: InChIKey=MZCUUFQUSDMWRT-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD+] (Homo sapiens (Human))	BDBM118049 (US8637558, 77) Show SMILES OC1=NC(=O)C(S1)=Cc1cc(F)c(OCCC2CCCCC2)c(Cl)c1 |w:7.8,t:1| Show InChI InChI=1S/C18H19ClFNO3S/c19-13-8-12(10-15-17(22)21-18(23)25-15)9-14(20)16(13)24-7-6-11-4-2-1-3-5-11/h8-11H,1-7H2,(H,21,22,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	177	n/a	n/a	n/a	n/a	7.5	n/a
Industry-Academic Cooperation Foundation, Chosun University US Patent					Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...				US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F
					More data for this Ligand-Target Pair