BDBM118068 US8637558, 102

SMILES: COc1cc(C=C2SC(O)=NC2=O)ccc1OCCc1cccs1

InChI Key: InChIKey=ZOPGBOGFULRHEH-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 118068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD(+)] (Homo sapiens (Human))	BDBM118068 (US8637558, 102) Show SMILES COc1cc(C=C2SC(O)=NC2=O)ccc1OCCc1cccs1 |w:5.4,c:9| Show InChI InChI=1S/C17H15NO4S2/c1-21-14-9-11(10-15-16(19)18-17(20)24-15)4-5-13(14)22-7-6-12-3-2-8-23-12/h2-5,8-10H,6-7H2,1H3,(H,18,19,20)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	682	n/a	n/a	n/a	n/a	7.5	n/a
Industry-Academic Cooperation Foundation, Chosun University US Patent					Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...				US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F
					More data for this Ligand-Target Pair