BDBM118073 CHEMBL2414145::US8637558, 108

SMILES: OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCC2)c(Cl)c1

InChI Key: InChIKey=NQQWAAXAZQXVCG-UHFFFAOYSA-N

Data: 2 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 118073   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
15-hydroxyprostaglandin dehydrogenase [NAD+] (Homo sapiens (Human))	BDBM118073 (CHEMBL2414145 | US8637558, 108) Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCC2)c(Cl)c1 |w:7.8,t:1| Show InChI InChI=1S/C17H18ClNO3S/c18-13-9-12(10-15-16(20)19-17(21)23-15)5-6-14(13)22-8-7-11-3-1-2-4-11/h5-6,9-11H,1-4,7-8H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	99.3	n/a	n/a	n/a	n/a	7.5	n/a
Industry-Academic Cooperation Foundation, Chosun University US Patent					Assay Description Experimental was performed by measuring the formation of NADH at 340 nm with a fluorescence spectrophotometer. Specifically, 2 ml (in total) of the s...				US Patent US8637558 (2014) BindingDB Entry DOI: 10.7270/Q280519F
					More data for this Ligand-Target Pair
15-hydroxyprostaglandin dehydrogenase [NAD+] (Homo sapiens (Human))	BDBM118073 (CHEMBL2414145 | US8637558, 108) Show SMILES OC1=NC(=O)C(S1)=Cc1ccc(OCCC2CCCC2)c(Cl)c1 |w:7.8,t:1| Show InChI InChI=1S/C17H18ClNO3S/c18-13-9-12(10-15-16(20)19-17(21)23-15)5-6-14(13)22-8-7-11-3-1-2-4-11/h5-6,9-11H,1-4,7-8H2,(H,19,20,21)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
Chungbuk National University Curated by ChEMBL					Assay Description Inhibition of human GST-fused 15-PGDH expressed in Escherichia coli BL21 using PGE2 as substrate assessed as formation of NADH by fluorescence spectr...				Bioorg Med Chem 21: 4477-84 (2013) Article DOI: 10.1016/j.bmc.2013.05.049 BindingDB Entry DOI: 10.7270/Q2542Q00
					More data for this Ligand-Target Pair